In a new chat about the film, Vaughn threw around a few ideas regarding a possible sequel to the prequel. On how First Class 2 could open, Vaughn said: “I thought it would be fun to open with the Kennedy Assassination, and we reveal that the magic bullet was controlled by Magneto.” Continuing that a First Class 2 wouldn’t necessarily follow the traditional comic-book sequel route of adding more characters to its roster, Vaughn added;“We will only have one more new character. I won’t say who he… I won’t say who he or she is! But we will only be bringing one more new character in, because, I think, as Professor X is in a wheelchair, Magneto needs to have a nemesis he can fight with. Someone that will be his equal. I know who it is. It would be nice if I could say something, but I can’t, mate!” Vaughn has speculated that a sequel could be set in "in the latter part of the 1960s where you’ve got The Stones, The Beatles, Flower Power." Actor James McAvoy expressed interest in seeing Charles Xavier get “really messed up” in the sequel and speculated that a third film could show his transition into a character closer to the one played by Patrick Stewart in the original trilogy. Michael Fassbender has said that he is "very excited" about the possibility of a sequel. He has said: "We worked very hard. It was a very trying time. Thank god, James is a good guy a very smart guy and he's a very practical guy. Matthew's great because he makes films as a fan. There's something like a nine-year-old boy in him when he's making a film. He's very much into characters and allowing the characters to drive the plot and the plot to drive the action film, as opposed to action driving the film and threading in some sort of a plot. It was a very rewarding experience, so hopefully we'll get the same team back again." Producer Lauren Shuler Donner has said that the sequel may be set in the 1970s. Writer and executive producer Bryan Singer has stated that it could be set around the Civil rights movement or the Vietnam War, and that Wolverine could once again be featured. Hugh Jackman has said that he would like to return. Simon Kinberg who co-wrote X-Men: The Last Stand and co-produed X-Men: First Class will write The Sequel.
Actress Jennifer Lawrence has expressed interest in reprising her role as Mystique in a sequel. Rose Byrne and Álex González revealed that they had signed on for two more films in the X-Men franchise. January Jones has said that she would love do another film. Lucas Till has said that he would like to reprise the role of Havok. Jason Flemyng has expressed interest in exploring the origins of Nightcrawler.
